Direkt zum Inhalt
Merck

GABBR2

gamma-aminobutyric acid (GABA) B receptor, 2

Synonyme:
GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9568) Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
  • Mouse(242425) gamma-aminobutyric acid (GABA) B receptor, 2
  • Rat(83633) gamma-aminobutyric acid (GABA) B receptor 2
  • domestic guinea pig(100170764) gamma-aminobutyric acid (GABA) B receptor, 2
  • naked mole-rat(101719923) gamma-aminobutyric acid (GABA) B receptor, 2
  • Horse(100063963) gamma-aminobutyric acid (GABA) B receptor, 2
  • sheep(101103544) gamma-aminobutyric acid (GABA) B receptor, 2
  • Domestic Rabbit(100346845) gamma-aminobutyric acid (GABA) B receptor, 2
  • domestic cat(101093058) gamma-aminobutyric acid (GABA) B receptor, 2
  • cow(517040) gamma-aminobutyric acid (GABA) B receptor, 2
  • dog(481627) gamma-aminobutyric acid (GABA) B receptor, 2
  • Zebrafish(560267) gamma-aminobutyric acid (GABA) B receptor, 2
  • chicken(420979) gamma-aminobutyric acid (GABA) B receptor, 2

Custom & Knockdown Gene Products

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Baclofen, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Baclofen, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Baclofen, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Baclofen, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
(±)-Baclofen, ≥98% (HPLC), solid,
Spezies
human, rat

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
CGP-13501, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
2-Hydroxysaclofen, ≥98% (TLC), solid,
Spezies
human
Phaclofen, solid,
Spezies
human
(±)-Baclofen, ≥98% (HPLC), solid,
Spezies
human, rat
Saclofen, solid,
Spezies
mouse, human, rat
4-Aminobutansäure, ≥99%,
Spezies
human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti GABBR2 Antibody, clone 23GB5500, Rabbit Monoclonal, clone 23GB5500, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
western blot
Anti-GABA B Receptor R2 Antibody, serum, from guinea pig,
Speziesreaktivität
bovine, canine, chimpanzee, horse, human, mouse, rat, rhesus macaque, rhesus monkey
Anwendung
immunohistochemistry
western blot
Anti-GABAB Receptor 2 in Kaninchen hergestellte Antikörper, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
rat
Anwendung
western blot
Monoclonal Anti-Gaba-B Receptor 2 - Rpe antibody produced in mouse, clone S81-2, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-GABBR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
NO-711 hydrochloride, ≥98% (HPLC),
Spezies
human
(±)-Vigabatrin, ,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GABBR2,
Spezies
human