The stability of this compound in solution has not been determined. However, various sources recommend that solutions not be stored for more than 1 day. If necessary, stock solutions may be stored in aliquots at -20°C for up to 1 month. This information has not been validated.
P4620
PD 146176
≥98% (HPLC), solid
Synonym(s):
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | Please contact Customer Service for Availability | CZK 5,000.00 CZK 4,250.00 | |
| 25 mg | Please contact Customer Service for Availability | CZK 16,000.00 |
About This Item
Empirical Formula (Hill Notation):
C15H11NS
CAS Number:
Molecular Weight:
237.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
CZK 4,250.00
List PriceCZK 5,000.00Save 15%Please contact Customer Service for Availability
Quality Level
assay
≥98% (HPLC)
form
solid
color
white to beige
solubility
DMSO: soluble >10 mg/mL, H2O: insoluble
SMILES string
C1Sc2ccccc2-c3[nH]c4ccccc4c13
InChI
1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChI key
ZGOOPZVQMLHPFM-UHFFFAOYSA-N
Gene Information
human ... ALOX15(246)
mouse ... ALOX15(11687)
rat ... ALOX15(81639)
Application
PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Biochem/physiol Actions
15-Lipoxygenase inhibitor
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
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This Item | |||
|---|---|---|---|
| form solid | form solid | form solid | form solid |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| solubility DMSO: soluble >10 mg/mL, H2O: insoluble | solubility DMSO: >10 mg/mL, H2O: insoluble | solubility DMSO: 18 mg/mL, H2O: insoluble | solubility DMSO: >10 mg/mL |
| color white to beige | color - | color red | color white to off-white |
| Gene Information human ... ALOX15(246) | Gene Information human ... CASP1(834), CASP3(836), CASP6(839), CASP7(840), SUMO1(7341) | Gene Information - | Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363) |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Elias I, et al.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P4620-5MG | 04061832785844 |
| P4620-25MG | 04061834374916 |
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Buongiorno, dopo aver risospeso la polvere, dove è meglio conservarla? Grazie
1 answer-
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