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L131

L-745,870 hydrochloride

Synonym(s):

3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine hydrochloride

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Size/SKUAvailabilityPrice
5 mg
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CZK 8,000.00
25 mg
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CZK 23,500.00
CZK 19,975.00

About This Item

Empirical Formula (Hill Notation):
C18H19ClN4 · HCl
CAS Number:
Molecular Weight:
363.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid

CZK 8,000.00


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form

solid

Quality Segment

color

white

solubility

H2O: 0.2 mg/mL, ethanol: 1.4 mg/mL, 0.1 M HCl: 5.5 mg/mL

SMILES string

Cl.Clc1ccc(cc1)N2CCN(CC2)Cc3c[nH]c4ncccc34

InChI

1S/C18H19ClN4.ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;/h1-7,12H,8-11,13H2,(H,20,21);1H

InChI key

GFFJYISJZJIKAF-UHFFFAOYSA-N

Gene Information

human ... DRD4(1815)

Biochem/physiol Actions

Selective D4 dopamine receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold under license from Merck & Co., Inc., Kenilworth, NJ, U.S. for use solely for preclinical researchy purposes (i.e., not for the administration to or other use in humans).

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This Item
G119A9736SML0588
form

solid

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: 0.2 mg/mL, 0.1 M HCl: 5.5 mg/mL, ethanol: 1.4 mg/mL

solubility

DMSO: 0.39 mg/mL, ethanol: 0.4 mg/mL, 0.1 M HCl: 0.68 mg/mL, methanol: 1 mg/mL, H2O: >10 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: 15 mg/mL, clear

color

white

color

yellow

color

white to beige

color

white to beige

Gene Information

human ... DRD4(1815)

Gene Information

human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)

Gene Information

-

Gene Information

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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