F5421

Anti-Fibroblast Growth Factor Receptor-1 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-FGFR-1
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD00675556
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC (p), IP, WB
• Citations: 9

Properties

• biological source: rabbit
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 110-120 kDa
• species reactivity: human
• packaging: antibody small pack of 25 μL
• concentration: ~1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using trypsin-digested human and animal tissue sections, immunoprecipitation (IP): suitable, western blot: 1:400 using an extract of FGFR-1 transfected cells
• UniProt accession no.: P11362
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FGFR1(2260)

Description

General description

Fibroblast growth factor receptor 1 (FGFR-1) belongs to the family of FGFRs. At the mRNA level, FGFR-1 is highly expressed in developing human tissues including the brain (preferentially in neurons), vascular basement membranes, skin, and bone growth plates.

Immunogen

Synthetic peptide corresponding to amino acid residues 360-373 of the extracellular region of human FGFR-1 conjugated to KLH with glutaraldehyde, and with a C-terminally added lysine.

Application

Anti-Fibroblast Growth Factor Receptor-1 antibody produced in rabbit has been used in:

• immunoprecipitation
• immunofluorocytochemistry
• immunohistochemistry
• immunoblotting

Biochem/physiol Actions

Anti-FGFR-1 antibody is specific for human FGFR-1 and does not react with human FGFR-2 and FGFR-3. The immunizing peptide specifically inhibits the staining of anti-FGFR-1 antibody.
Staining of the product is specifically inhibited with the FGFR-1 immunizing peptide. No reaction with human FGFR-2 and FGFR-3 is detected.

No reaction with FGFR-2 (Bek) and FGFR-3 is detected.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable