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Merck

A6428

Aflatoxin M1

From Aspergillus flavus, , mycotoxin, film

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5 μG

CZK 4,440.00

10 μG

CZK 6,570.00

50 μG

CZK 19,040.00

250 μG

CZK 62,700.00

CZK 4,440.00


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About This Item

Empirical Formula (Hill Notation):
C17H12O7
CAS Number:
Molecular Weight:
328.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
229-865-4
MDL number:
Form:
film
Quality level:

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Product Name

Aflatoxin M1, from Aspergillus flavus

biological source

Aspergillus flavus

Quality Level

form

film

storage temp.

2-8°C

SMILES string

[H][C@]12OC=C[C@@]1(O)c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1

InChI key

MJBWDEQAUQTVKK-IAGOWNOFSA-N

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This Item
A6655A0138A9441
form

film

form

powder

form

powder

form

dry concentrate

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

biological source

Aspergillus flavus

biological source

-

biological source

Aspergillus flavus

biological source

-

General description

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods. Aflatoxin M1 is a hydroxylated metabolite of aflatoxin B1. It is liberated in milk, urine and produced in liver after receiving aflatoxin B1.

Application

Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.
Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in Brazilian milk and infant formula. It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in dairy products produced in Brazil.

Biochem/physiol Actions

Aflatoxin M1 possesses hepatocarcinogenic properties.

Preparation Note

Aspergillus flavus metabolite.

Disclaimer

Possibly carcinogenic.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Carc. 1B - Muta. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Aflatoxins
Handbook of Secondary Fungal Metabolites, 545-569 (2003)
Nathalie Paniel et al.
Sensors (Basel, Switzerland), 10(10), 9439-9448 (2010-01-01)
We have developed an electrochemical immunosensor for the detection of ultratrace amounts of aflatoxin M(1) (AFM(1)) in food products. The sensor was based on a competitive immunoassay using horseradish peroxidase (HRP) as a tag. Magnetic nanoparticles coated with antibody (anti-AFM(1))
Aflatoxins
Handbook of Secondary Fungal Metabolites (2003)
Aflatoxin M1 in milk and distribution and stability of aflatoxin M1 during production and storage of yoghurt and cheese
Iha MH, et al.
Food Control, 29(1), 1-6 (2013)
Occurrence of aflatoxin M1 in dairy products in Brazil
Iha MH, et al.
Food Control, 22(12), 1971-1974 (2011)

Articles

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Global Trade Item Number

SKUGTIN
A6428-250UG04061832938837
A6428-10UG04061833382257
A6428-50UG04061835381128
A6428-5UG04061833382264

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