A6655
Aflatoxin B₁−BSA Conjugate
from Aspergillus flavus, powder, hepatotoxic mycotoxin
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5 MG
CZK 11,400.00
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5 MG
CZK 11,400.00
About This Item
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Product Name
Aflatoxin B1−BSA Conjugate from Aspergillus flavus,
form
powder
Quality Level
extent of labeling
8-12 mol Aflatoxin B1 per mol BSA
storage temp.
2-8°C
General description
Aflatoxin B1 is the most toxic aflatoxin.[1] Aflatoxins are hepatotoxic metabolites,[2] that are produced by molds, such as Aspergillus flavus and Aspergillus parasiticus.[3] Aflatoxins contaminate human food and animal feed.[3] They are linked to liver cancer,[4] immune system suppression, reduced growth rates, losses in feed efficiency and death.[3] They are naturally found toxic carcinogens and the most widely known mycotoxins. They mainly contaminate fruits, vegetables and grains.[4]
Application
Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene.
Warning
Possibly carcinogenic.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P Sizaret et al.
Journal of the National Cancer Institute, 69(6), 1375-1381 (1982-12-01)
Rabbit (outbred albino New Zealand White) antisera have been raised against aflatoxin B1 (AFB1) using as immunogen conjugates in which the hapten was coupled to bovine serum albumin (BSA) either through C1 or C8 with the oxime and the dichloride
P Sizaret et al.
Journal of immunological methods, 63(2), 159-162 (1983-10-14)
We reported previously on the properties of an anti-aflatoxin B1 (AFB) antiserum raised with a conjugate in which AFB is coupled at the C8 position to bovine serum albumin (BSA). The hapten/carrier protein molar ratio of the conjugate was 14.
Review of past and present research on Aflatoxin in Uganda
Kaaya NA and Warren HL
African Journal of Food, Agriculture, Nutrition and Development, 5(1), 425-428 (2005)
Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Regional differences in production of aflatoxin B1 and cyclopiazonic acid by soil isolates of Aspergillus flavus along a transect within the United States
Horn BW and Dorner JW
Applied and Environmental Microbiology, 65(4), 1444-1449 (1999)
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