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44977

DISBAC2(3), Voltage Sensitive Probe

≥98% (HPLC)

Synonym(s):

5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol

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Pack SizeSKUAvailabilityPrice
1 mg
Please contact Customer Service for Availability
CZK 16,300.00

About This Item

Empirical Formula (Hill Notation):
C19H24N4O4S2
CAS Number:
47623-98-3
Molecular Weight:
436.55
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
329756577
EC Number:
256-325-5
Beilstein/REAXYS Number:
1232950
MDL number:
MFCD07437858

CZK 16,300.00

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Quality Level

100

assay

≥98% (HPLC)

fluorescence

λex 535 nm; λem 560 nm in DMSO

suitability

complies for Infrared spectrum

storage temp.

−20°C

SMILES string

CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S

InChI

1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+

InChI key

VJYNRXFXHKIGLT-MDZDMXLPSA-N

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This Item
930709SML2683901099
DISBAC2(3), Voltage Sensitive Probe ≥98% (HPLC)

Sigma-Aldrich

44977

DISBAC2(3), Voltage Sensitive Probe

Pomalidomide-piperazine-propanoic acid ≥95.0%

Sigma-Aldrich

930709

Pomalidomide-piperazine-propanoic acid

dBET6 ≥98% (HPLC)

Sigma-Aldrich

SML2683

dBET6

PBDB-T

Sigma-Aldrich

901099

PBDB-T

suitability

complies for Infrared spectrum

suitability

-

suitability

-

suitability

-

fluorescence

λex 535 nm; λem 560 nm in DMSO

fluorescence

-

fluorescence

-

fluorescence

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

assay

≥98% (HPLC)

assay

≥95.0%

assay

≥98% (HPLC)

assay

-

Application

DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0621
BCCF8360
BCCD1917
BCBH2187V

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M K Tanner et al.
Cytometry, 14(1), 59-69 (1993-01-01)
Immunosuppression by the fungal metabolite cyclosporin A (CsA) is characterized by functional inhibition, rather than destruction of cells. Because activation of immune cells involves intracellular signalling events associated with modulations of cell transmembrane potential (TMP), we tested the ability of
Alexander S Tatikolov et al.
Biophysical chemistry, 107(1), 33-49 (2004-02-12)
Non-covalent interactions between polymethine dyes of various types (cationic and anionic thiacarbocyanines as well as anionic oxonols and tetracyanopolymethines) and human serum albumin (HSA) were studied by means of absorption, fluorescence and circular dichroism (CD) spectroscopies. Complexation with the protein
N Minami et al.
Journal of neural transmission. General section, 97(1), 65-72 (1994-01-01)
Effects of cyclic AMP on membrane potentials were examined by measuring the changes of bis-oxonol fluorescence in bovine adrenal medullary chromaffin cells. 8-Bromo cyclic AMP (8Br-cAMP) or forskolin caused a gradual and long lasting increase of the fluorescence intensity. The
In situ study of the membrane potential in microvascular endothelial cells using a fluorescent probe.
K Miao et al.
Microvascular research, 48(1), 135-142 (1994-07-01)
S Amoroso et al.
Biochimica et biophysica acta, 1239(1), 67-73 (1995-10-04)
In this study the effect of the A1 agonist 2-chloro-N6-cyclopentyladenosine (CCPA) on bis(1,3-diethylthiobarbituric acid)trimethine oxonol (bisoxonol)-monitored membrane potential in cerebrocortical nerve endings was evaluated. CCPA (30, 100 and 300 microM) caused a dose-dependent decrease of high K(+)- and veratridine-induced membrane
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Global Trade Item Number

SKUGTIN
44977-1MG04061823367226

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