00017

Acacetin

≥97.0% (HPLC)

• Synonym(s): 4′-Methylapigenin, 5,7-Dihydroxy-4′-methoxyflavone, Apigenin 4′-methyl ether, Buddleoflavonol, Linarigenin
• Empirical Formula (Hill Notation): C₁₆H₁₂O₅
• CAS Number: 480-44-4
• Molecular Weight: 284.26
• PubChem Substance ID: 329746990
• eCl@ss: 32150233
• UNSPSC Code: 12352200
• NACRES: NA.47
• EC Number: 207-552-3
• MDL number: MFCD00016936
• Beilstein/REAXYS Number: 277879

Properties

• Quality Segment: 100
• assay: ≥97.0% (HPLC)
• form: powder or crystals
• mp: 260-265 °C (lit.)
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: COc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C16H12O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-8,17-18H,1H3
• InChI key: DANYIYRPLHHOCZ-UHFFFAOYSA-N

Description

General description

Acacetin belongs to the category of naturally occurring plant pigments called flavonoids found in vascular plants. It was first reported to be extracted from the leaves of Robinia pseuducacia. It has been used as an active component of traditional Chinese medicine Xuelianhua.

Biochem/physiol Actions

Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine.

Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine. It has been recognized as an antiproliferative agent on cancer cell lines by inducing apoptosis and blocking cell cycle progression in the G1 phase.

Acacetin has been noted to exhibit anti-peroxidative, anti-inflammatory, and anti-plasmodial properties. It has been posited to prevent the proliferation of Hep G2 cells, thereby causing cell apoptosis and subsequent anti-cancer action. It has antiarrhythmic properties and can be used in the treatment of Atrial fibrillation.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves