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Anti-8-Hydroxyguanosine Goat pAb

Name: Anti-8-Hydroxyguanosine Goat pAb
Brand: MM

liquid, Calbiochem^®

Synonym(s):

Anti-8-OHG, Anti-8-oxo-G

About This Item

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

Application:

—

Citations:

This product is discontinued. Contact Technical Servicefor assistance.

Properties

biological source

goat

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity (predicted by homology)

all

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:250,000)
Paraffin Sections (1:200, proteinase K pre-treatment recommended; see figure legend, )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Description

General description

Goat polyclonal antibody supplied as undiluted serum. Recognizes 8-hydroxydeoxy-guanosine.

Recognizes 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue.

This Anti-8-Hydroxyguanosine Goat polyclonal antibody detects 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue. It is validated for use in ELISA and with paraffin sections.

Immunogen

8-Hydroxyguanosine

Application

ELISA (≥1:250,000)
Paraffin Sections (≥1:200, proteinase K pre-treatment recommended; see figure legend, see application references)

Physical form

Undiluted serum.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Positive Control
Alzheimer’s disease brain tissue

Other Notes

Abe, T., et al. 2003. Neurosci. Lett.336, 105.
Parker, A.R., et al. 2002. Cancer Res.62, 7230.

Does not cross-react with other naturally occurring nucleotides. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Compare Similar Items

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Show Differences

1 of 1

This Item	178479	DR1015	AB5830
Sigma-Aldrich DR1001 Anti-8-Hydroxyguanosine Goat pAb	Sigma-Aldrich 178479 Anti-Apolipoprotein E Goat pAb	Sigma-Aldrich DR1015 Anti-RENT1 Goat pAb	Sigma-Aldrich AB5830 Anti-8-Hydroxydeoxyguanosine Antibody
biological source goat	biological source goat	biological source goat	biological source goat
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form serum	antibody form serum	antibody form affinity isolated antibody	antibody form serum
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in dry ice
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
form liquid	form liquid	form liquid	form -

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.

N Gueven et al.

Cell death and differentiation, 14(6), 1149-1161 (2007-03-10)

Several different autosomal recessive genetic disorders characterized by ataxia with oculomotor apraxia (AOA) have been identified with the unifying feature of defective DNA damage recognition and/or repair. We describe here the characterization of a novel form of AOA showing increased

Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype.

Joseph J Boyle et al.

The American journal of pathology, 174(3), 1097-1108 (2009-02-24)

Intraplaque hemorrhage accelerates atherosclerosis via oxidant stress and contributes to lesion development and destabilization. Normally, macrophages scavenge hemoglobin-haptoglobin (HbHp) complexes via CD163, and this process provokes the secretion of the anti-inflammatory atheroprotective cytokine interleukin (IL)-10. We therefore tested the hypothesis

Global Trade Item Number

SKU	GTIN
DR1001-100UL	04055977225884

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