SML3811

Hygromycin A

≥98% (HPLC)

• Synonyma: Totomycin, 5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-D-neo-inositol, Homomycin, Hygromycin
• Empirický vzorec (Hillův zápis): C₂₃H₂₉NO₁₂
• Číslo CAS: 6379-56-2
• Molekulová hmotnost: 511.48
• UNSPSC Code: 51111800
• UNSPSC Code: 12352200
• NACRES: NA.21

Vlastnosti

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: O[C@H]1[C@]2([H])[C@@]([C@@H]([C@@H]([C@@H]1O)NC(/C(C)=C/C3=CC=C(C(O)=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)([H])OCO2

Popis

Biochem/physiol Actions

Hygromycin A is an orally available antibiotic produced by Streptomyces hygroscopicus that targets the ribosomal 23S rRNA. Hygromycin A is selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi, which causes Lyme disease. It clears B. burgdorferi infection in mice with lesser disruption of micron=biome than clinical antibiotics.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable