SML3655

LockdownPro

≥97% (HPLC)

• Synonyma: Tetraethyl 4,4′-((propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalate
• Empirický vzorec (Hillův zápis): C₃₉H₄₀O₁₀
• Molekulová hmotnost: 668.73
• UNSPSC Code: 12352200
• NACRES: NA.25

Vlastnosti

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: (oil or liquid)
• color: colorless to yellow
• storage temp.: 2-8°C
• SMILES string: CC(C1=CC=C(C=C1)OC2=CC(C(OCC)=O)=C(C(OCC)=O)C=C2)(C3=CC=C(OC4=CC(C(OCC)=O)=C(C(OCC)=O)C=C4)C=C3)C
• InChI: 1S/C39H40O10/c1-7-44-35(40)31-21-19-29(23-33(31)37(42)46-9-3)48-27-15-11-25(12-16-27)39(5,6)26-13-17-28(18-14-26)49-30-20-22-32(36(41)45-8-2)34(24-30)38(43)47-10-4/h11-24H,7-10H2,1-6H3
• InChI key: ROEOSYBNNXMANC-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

Cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F that inhibits tissue invasion by PPM1F-overexpressing human cancer cells

LockdownPro, an esterified lockdown analog with better cell permeability, is a cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F. LockdownPro potently inhibits tissue invasion by PPM1F-overexpressing human cancer cells. It does not inhibit PPM1F in vitro.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable