SML3593

Hexachlorophene

≥95% (HPLC)

• Synonyma: 2,2′,3,3′,5,5′-Hexachloro-6,6′-dihydroxydiphenylmethane, 2,2′-Dihydroxy-3,3′,5,5′,6,6′-hexachlorodiphenylmethane, 2,2′-Methylenebis[3,4,6-trichlorophenol], Nabac
• Empirický vzorec (Hillův zápis): C₁₃H₆Cl₆O₂
• Číslo CAS: 70-30-4
• Molekulová hmotnost: 406.90
• MDL number: MFCD00002171
• UNSPSC Code: 12352200
• NACRES: NA.04

Vlastnosti

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: ClC1=C(C(O)=C(C=C1Cl)Cl)CC2=C(C(Cl)=CC(Cl)=C2O)Cl
• InChI key: ACGUYXCXAPNIKK-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

Hexachlorophene is selective and potent N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor. Hexachlorophene potently inhibits NAPE-PLD activity in cultured HEK293 cells. Hexachlorophene is an antibacterial compound used topically by health-care personnel to control cutaneous gram-positive infections. Also it appears that hexachlorophene is an inhibitor of virus entry for Severe fever with thrombocytopenia syndrome virus (SFTSV).

Selective and potent N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor; topical anti-bacterial agent

Bezpečnostní informace

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H301 + H311,H410
• pcodes: P264 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P361 + P364
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable