SML2141

Solifenacin succinate

≥98% (HPLC)

• Synonyma: (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4­dihydro-1-phenyl-2(1H)-iso-quinolinecarboxylate succinate, YM905
• Empirický vzorec (Hillův zápis): C₂₃H₂₆N₂O₂ · C₄H₆O₄
• Číslo CAS: 242478-38-2
• Molekulová hmotnost: 480.55
• MDL number: MFCD00954234
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +35 to +45°, c = 1 in H₂O
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3
• InChI: 1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1
• InChI key: RXZMMZZRUPYENV-DZSUWJOWSA-N

Popis

Biochem/physiol Actions

Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.

Bezpečnostní informace

• pictograms: GHS08
• signalword: Warning
• hcodes: H361d
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable