SML0651

OAC1

≥98% (HPLC)

• Synonyma: N-1H-Pyrrolo[2,3-c]pyridin-5-yl-benzamide
• Empirický vzorec (Hillův zápis): C₁₄H₁₁N₃O
• Číslo CAS: 300586-90-7
• Molekulová hmotnost: 237.26
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [nH]1c2c(cc1)cc(nc2)NC(=O)c3ccccc3
• InChI: 1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
• InChI key: HWJRIFZDXJKJJN-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

OAC1 enhances iPSC reprogramming efficiency by enhancing Oct4 and Nanog driven gene expression. Treatment of mouse embryonic fibroblasts transduced with Oct2, Sox2, Klf4 and c-myc displayed a two-fold increase in the formation of ESC-like clones. OAC1 treated cells display a hypomethylated state of Oct4 promoter DNA.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable