About This Item
Empirický vzorec (Hillův zápis):
C49H71N13O10
Molekulová hmotnost:
1002.17
UNSPSC Code:
12352209
NACRES:
NA.32
Doporučené produkty
![[Asn1, Val5]-Angiotensin II ≥97% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/380/827/d4959a32-f11c-488c-9bc0-86d4d43cb5cb/640/d4959a32-f11c-488c-9bc0-86d4d43cb5cb.png)
![[Val5]-Angiotensin II acetate salt hydrate ≥95% (HPLC), powder](/deepweb/assets/sigmaaldrich/product/structures/301/478/c093dfb8-a891-46ac-b6a1-655b77da7c03/640/c093dfb8-a891-46ac-b6a1-655b77da7c03.png)
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥65%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Sar-Arg-Val-Tyr-Ile-His-Pro-Phe
Application
Angiotensins are peptide hormone components of the renin-angiotensin system involved in the regulation of blood vessel constriction and aldosterone release. Angiotensin I, a decapeptide derived from angiotensinogen, is a converted to Angiotensin II by the removal of the two C-terminal amino acids. Various analogues of Angiotensins I and II made by amino acid substitution are used in structure and sequence studies to analyze and differentiate the functions of natural angiotensins.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Vani X Oliveira et al.
Regulatory peptides, 172(1-3), 1-7 (2011-07-27)
Angiotensin II (AII) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. In an attempt to establish the AII-receptor-bound conformation of this octapeptide, we designed conformationally constrained analogues by scanning the entire
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