SAB4502136

Anti-PDGFB antibody produced in rabbit

affinity isolated antibody

• Synonyma: PDGF subunit B, PDGF-2, Platelet-derived growth factor β polypeptide, Platelet-derived growth factor B chain, Platelet-derived growth factor subunit B
• UNSPSC Code: 12352203
• NACRES: NA.41

Vlastnosti

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 27 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; western blot: 1:500-1:1000
• NCBI accession no.: P01127
• UniProt accession no.: P01127
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PDGFB(5155)

Popis

General description

Anti-PDGFB Antibody detects endogenous levels of total PDGFB protein.

The platelet derived growth factor receptor β (PDGFRB) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.

Immunogen

The antiserum was produced against synthesized peptide derived from human PDGFB.

Immunogen Range: 16-65

Biochem/physiol Actions

Platelet derived growth factor receptor β (PDGFRB) acts as a regulator of mesenchymal cells in tumor cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Bezpečnostní informace

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable