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Key Documents

RAB0220

Sigma-Aldrich

Mouse ICAM-1 ELISA Kit

for serum, plasma and cell culture supernatant

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.69-6000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Icam1(15894)

General description

The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Mouse ICAM1

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel. ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases. IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells. ICAM-1 causes invasion and metastasis of breast cancer cells. ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Součásti soupravy, které jsou dostupné také samostatně

Č. produktu
Popis
Bezpečností list

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)Bezpečností list

  • RABELADDELISA 5X Assay/Sample Diluent Buffer D (Item K)Bezpečností list

  • RABSTOP3ELISA Stop Solution (Item I)Bezpečností list

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Bezpečností list

  • RABWASH420X Wash Buffer (Item B)Bezpečností list

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials


Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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Navštívit knihovnu dokumentů

The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)
Shukla SD, et al.
Respiratory Research, 18(1), 6-6 (2017)
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
Lin YM, et al.
Cancer Letters, 328(1), 135-143 (2013)
Role of ICAM1 in invasion of human breast cancer cells
Rosette C, et al.
Carcinogenesis, 26(5), 943-950 (2005)
ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease
Liu A, et al.
Medicine, 97(40), e12523-e12523 (2018)
Jochen G Schneider et al.
International journal of cardiology, 176(1), 139-144 (2014-08-03)
Coagulation and prothrombotic potential have genuinely been associated with increased cardiovascular risk. However, not all studies in this regard are conclusive. Some clinical trials have shown an increased frequency of cardiovascular complications in patients receiving direct thrombin inhibitors. Previous data

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