PZ0273

PF-04531083

≥98% (HPLC)

• Synonyma: N-[6-Amino-5-(2-chloro-5-methoxyphenyl)-2-pyridinyl]-1-methyl-1H-pyrazole-5-carboxamide, N-[6-Amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-1-methyl-1H-pyrazole-5-carboxamide, PF 4531083
• Empirický vzorec (Hillův zápis): C₁₇H₁₆ClN₅O₂
• Číslo CAS: 1079400-07-9
• Molekulová hmotnost: 357.79
• UNSPSC Code: 51111800
• NACRES: NA.77

Vlastnosti

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: room temp
• SMILES string: Clc1c(cc(cc1)OC)c2c(nc(cc2)NC(=O)c3[n](ncc3)C)N
• InChI: 1S/C17H16ClN5O2/c1-23-14(7-8-20-23)17(24)22-15-6-4-11(16(19)21-15)12-9-10(25-2)3-5-13(12)18/h3-9H,1-2H3,(H3,19,21,22,24)
• InChI key: ZRJGMDIPCQOGNI-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

PF-04531083 is an orally available, potent and selective sodium channel Nav1.8 blocker. PF-04531083 was designated as a potential treatment of pain.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable