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P2172

Sigma-Aldrich

C-Phycocyanin from Spirulina sp.

lyophilized powder

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About This Item

Číslo CAS:
11016-15-2
MDL number:
MFCD00130691
UNSPSC Code:
12352202
NACRES:
NA.56

biological source

Spirulina

Quality Level

200

form

lyophilized powder

composition

Protein, ~40% Lowry

concentration

30-50% protein (Lowry)

storage temp.

2-8°C

Gene Information

Spirulina ... cpcA(41380954) , cpcB(41380955)

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General description

C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.

Application

C-Phycocyanin from Spirulina sp. has been used:
  • as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
  • as a standard to confirm the antibacterial activity
  • to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
  • to identify the phycocyanin from water extracted Spirulina maxima sample

Biochem/physiol Actions

C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria.
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.

Packaging

Package size based on protein content

Physical form

Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number
0000363730
0000363730
0000308067
0000225272
0000225271

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Navštívit knihovnu dokumentů

Bing Li et al.
Biotechnology and applied biochemistry, 43(Pt 3), 155-164 (2005-12-01)
C-phycocyanin (C-PC), a water-soluble protein pigment, isolated from Spirulina platensis, is of great importance because of its various medical and pharmacological properties. In the present study, we first investigated the effect of highly purified C-PC on growth and proliferation of
Protective effect of water extracted Spirulina maxima on glutamate-induced neuronal cell death in mouse hippocampal HT22 cell
Lee HY, et al.
Pharmacognosy magazine, 14(54), 242-242 (2018)
Evaluating fluorescence spectroscopy as a tool to characterize cyanobacteria intracellular organic matter upon simulated release and oxidation in natural water
Korak JA, et al.
Water Research, 68(1), 432-443 (2015)
Screening of anti-bacterial activity of C-phycocyanin and its minimum inhibitory concentration (MIC) determination by agar dilution method
Murugan T and Madhavan R
Asian Journal of Biological Sciences, 6(1), 41-45 (2011)
Jun-Ichi Ishihara et al.
Biochemistry and biophysics reports, 34, 101469-101469 (2023-05-01)
The one-dimensional multicellular cyanobacterium, Anabaena sp. PCC 7120, exhibits a simple topology consisting of two types of cells under the nitrogen-depleted conditions. Although the differentiated (heterocyst) and undifferentiated cells (vegetative cells) were distinguished by their cellular shapes, we found that
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