K7125

(±)-3-Methyl-2-oxovaleric acid sodium salt

• Synonyma: (±)-Sodium 3-methyl-2-oxovalerate, 3-Methyl-2-oxopentanoic acid sodium salt, DL-α-Keto-β-methylvaleric acid sodium salt, Ketoisoleucine sodium salt
• Lineární vzorec: CH₃CH₂CH(CH₃)COCOONa
• Číslo CAS: 3715-31-9
• Molekulová hmotnost: 152.12
• Beilstein/REAXYS Number: 7779663
• EC Number: 266-503-4
• MDL number: MFCD00002584
• UNSPSC Code: 12352211
• PubChem Substance ID: 24896244
• NACRES: NA.25

Vlastnosti

• Quality Level: 200
• lipid type: saturated FAs
• storage temp.: 2-8°C
• SMILES string: [Na+].CCC(C)C(=O)C([O-])=O
• InChI: 1S/C6H10O3.Na/c1-3-4(2)5(7)6(8)9;/h4H,3H2,1-2H3,(H,8,9);/q;+1/p-1
• InChI key: SMDJDLCNOXJGKC-UHFFFAOYSA-M

Popis

Biochem/physiol Actions

(±)-3-Methyl-2-oxovaleric acid sodium salt is a mixture of the D- and L-3-methyl-2-oxovaleric acids. 3-methyl-2-oxovaleric acid is used as a substrate to study the specificity, distribution and kinetics of α-keto acid dehydrogenases. α-keto-β-methylvaleric acid is used to inhibit the mitochondrial α-ketoglutarate dehydrogenase complex (KGDHC) to induce and study nerve cell death. α-keto-β-methylvaleric acid may be studied as a reactive oxygen scavenger.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)