JN0004

Tolmetin sodium dihydrate

≥98% (HPLC)

• Synonyma: Tolmetin sodium salt dihydrate, 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid sodium salt dihydrate, Sodium 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetate dihydrate, 1-Methyl-5-(p-toluoyl)pyrrole-2-acetic acid sodium salt dihydrate
• Lineární vzorec: C₁₅H₁₄NO₃Na · 2H₂O
• Číslo CAS: 64490-92-2
• Molekulová hmotnost: 315.30
• MDL number: MFCD00150761
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: room temp
• SMILES string: [Na+].[H]O[H].[H]O[H].Cc1ccc(cc1)C(=O)c2ccc(CC([O-])=O)n2C
• InChI: 1S/C15H15NO3.Na.2H2O/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18;;;/h3-8H,9H2,1-2H3,(H,17,18);;2*1H2/q;+1;;/p-1
• InChI key: QQILXENAYPUNEA-UHFFFAOYSA-M
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Popis

Biochem/physiol Actions

Tolmetin sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthetase in vitro and reduces plasma levels of prostaglandin E. Tolmetin sodium exhibits anti-inflammatory, analgesic and antipyretic activity Its precise mechanism of is unknown. Tolmetin is used to treat rheumatoid arthritis, osteoarthrosis, pain, and ankylosing spondylitis.

Bezpečnostní informace

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361d
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable