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Hlavní dokumenty

I2753

Sigma-Aldrich

Inosine 3′:5′-cyclic monophosphate sodium salt

≥98%

Synonyma:

cIMP

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Lineární vzorec:
C10H10N4O7PNa
Číslo CAS:
Molekulová hmotnost:
352.17
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51

Quality Level

assay

≥98%

form

powder

storage temp.

−20°C

SMILES string

[Na].OC1C2OP(O)(=O)OCC2OC1n3cnc4C(=O)N=CNc34

InChI

1S/C10H11N4O7P.Na.H/c15-6-7-4(1-19-22(17,18)21-7)20-10(6)14-3-13-5-8(14)11-2-12-9(5)16;;/h2-4,6-7,10,15H,1H2,(H,17,18)(H,11,12,16);;

InChI key

XIUBZBACWHALEW-UHFFFAOYSA-N

Application

Inosine 3′:5′-cyclic monophosphate (cIMP) is used in studies that compare the substrate specificity and activity of cyclic purines, including the 3′,5′-cyclic monophosphates cAMP and cGMP.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Navštívit knihovnu dokumentů

Galen E Flynn et al.
The Journal of general physiology, 121(6), 563-582 (2003-05-29)
Cyclic nucleotide-gated (CNG) channels belong to the P-loop-containing family of ion channels that also includes KcsA, MthK, and Shaker channels. In this study, we investigated the structure and rearrangement of the CNGA1 channel pore using cysteine mutations and cysteine-specific modification.
Daisuke Okada et al.
Biochemistry, 41(30), 9672-9679 (2002-07-24)
The effects of cGMP binding on the catalytic activity of cGMP-specific, cGMP-binding phosphodiesterase (PDE5) are unclear because cGMP interacts with both allosteric and catalytic sites specifically. We studied the effects of cGMP on the hydrolysis of a fluorescent substrate analogue
R C Ganassin et al.
Journal of cellular physiology, 160(3), 409-416 (1994-09-01)
The influence of inosine on DNA synthesis by Chinook salmon embryo cells (CHSE-214) was investigated because previously cell number was shown to increase from six- to thirtyfold if inosine was added to the basal medium (L-15) supplemented with either dialyzed
Adam K Jagielski et al.
Archives of biochemistry and biophysics, 404(2), 186-196 (2002-07-31)
The effects of extracellular purinergic agonists and their breakdown products on glucose and glutamine synthesis in rabbit kidney-cortex tubules incubated with aspartate + glycerol or alanine + glycerol + octanoate were investigated. A rapid extracellular degradation of ATP was accompanied
Riegel et al.
The Journal of experimental biology, 201 (Pt 24), 3411-3418 (1998-11-18)
External application of the 3',5'-cyclic monophosphates of inosine, cytidine, uridine and thymidine stimulated the fluid secretion rate (FSR) of Malpighian tubules isolated from Drosophila melanogaster. The evidence suggested that the cyclic nucleotides acted intracellularly in some capacity. Receptors of the

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