E6511

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

BioReagent, suitable for cell culture, 98.5-102.0%

• Synonyma: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate
• Lineární vzorec: (NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · 2H₂O
• Číslo CAS: 10378-23-1
• Molekulová hmotnost: 416.20
• UNSPSC Code: 12352204
• NACRES: NA.75
• PubChem Substance ID: 24894629
• EC Number: 200-573-9
• Beilstein/REAXYS Number: 3861753
• MDL number: MFCD00150026

Vlastnosti

• product line: BioReagent
• Quality Segment: 200
• assay: 98.5-102.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 160 mg/mL
• shipped in: ambient
• storage temp.: room temp
• SMILES string: O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
• InChI key: KSYNLCYTMRMCGG-UHFFFAOYSA-J

Popis

General description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.

Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
• as a chelator in animal and testicular cell isolation
• as a chelator for the culture of neural stem cells[1]

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Bezpečnostní informace

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302 + H332,H318,H373
• pcodes: P260 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
• target_organs: Respiratory Tract
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves