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Y0001422

Valproic acid for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonyma:

2-Propylpentanoic acid, Valproic acid

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About This Item

Lineární vzorec:
(CH3CH2CH2)2CHCO2H
Číslo CAS:
99-66-1
Molekulová hmotnost:
144.21
MDL number:
MFCD00002672
UNSPSC Code:
41116107
PubChem Substance ID:
329831418
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

valproic acid

manufacturer/tradename

EDQM

refractive index

n20/D 1.425 (lit.)

bp

220 °C (lit.)

density

0.9 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCC(C(O)=O)CCC

InChI

1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

InChI key

NIJJYAXOARWZEE-UHFFFAOYSA-N

Gene Information

human ... ALDH5A1(7915)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Valproic acid for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

231.8 °F - closed cup

flash_point_c

111 °C - closed cup

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Osvědčení o analýze (COA)

Lot/Batch Number

Je nám líto, ale pro tento produkt momentálně nemáme COA k dispozici online.

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Sigma-Aldrich

676380

Valproic Acid, Sodium Salt

Sodium valproate European Pharmacopoeia (EP) Reference Standard

S0930000

Sodium valproate

Trichostatin A, Ready Made Solution 5 mM in DMSO, from Streptomyces sp.

Sigma-Aldrich

T1952

Trichostatin A, Ready Made Solution

Anton Pohanka et al.
Scandinavian journal of clinical and laboratory investigation, 74(7), 648-652 (2014-07-26)
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PloS one, 9(10), e108682-e108682 (2014-10-08)
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Archives of toxicology, 88(8), 1573-1588 (2014-02-19)
Liver injury is the leading cause of drug-induced toxicity. For the evaluation of a chemical compound to induce toxicity, in this case steatosis or fatty liver, it is imperative to identify markers reflective of mechanisms and processes induced upon exposure
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