Y0000155

Tramadol hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyma: (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
• Empirický vzorec (Hillův zápis): C₁₆H₂₅NO₂ · HCl
• Číslo CAS: 36282-47-0
• Molekulová hmotnost: 299.84
• MDL number: MFCD00798507
• UNSPSC Code: 41116107
• PubChem Substance ID: 329830868
• NACRES: NA.24

Vlastnosti

• grade: pharmaceutical primary standard
• API family: tramadol
• manufacturer/tradename: EDQM
• drug control: USDEA Schedule IV
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• InChI key: PPKXEPBICJTCRU-XMZRARIVSA-N

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Tramadol is a synthetic opiate agonist analgesic, widely used in patients suffering from moderate to severe chronic pain. It is considered safe when compared to other opioids. It contributes to the analgesic activity by blocking the nociceptive impulses at the spinal level, inhibiting the norepinephrine and serotonin reuptake.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Opioid analgesic; P450 substrate.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H301,H336,H411
• pcodes: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable