PHR1191

Nitrofurantoin

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: N-(5-Nitro-2-furfurylidene)-1-aminohydantoin, Furadoxyl, Nitrofurantoine
• Empirický vzorec (Hillův zápis): C₈H₆N₄O₅
• Číslo CAS: 67-20-9
• Molekulová hmotnost: 238.16
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329823199
• EC Number: 200-646-5
• Beilstein/REAXYS Number: 893207
• MDL number: MFCD00003224
• eCl@ss: 25140904

Vlastnosti

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to USP 1464001
• API family: nitrofurantoin
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care; pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: [O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1
• InChI: 1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
• InChI key: NXFQHRVNIOXGAQ-YCRREMRBSA-N

Popis

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Nitrofurantoin, a synthetic, nitrofuran-derivative, is a widely used urinary antimicrobial compound that is effective against pulmonary fibrosis, neuropathy, hepatitis and hemolytic anemia.

Application

Nitrofurantoin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by voltammetry and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

To see an example of a Certificate of Analysis for this material enter LRAA9007 in the slot below. This is an example certificate only and may not be the lot that you receive.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Bezpečnostní informace

• Piktogramy: GHS08,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H302,H317,H334
• Bezpečnostní pokyny: P280 - P301 + P312 + P330 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 1
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable