45313
Terbufos
PESTANAL®, analytical standard
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
Empirický vzorec (Hillův zápis):
C9H21O2PS3
Číslo CAS:
Molekulová hmotnost:
288.43
Beilstein/REAXYS Number:
1710115
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Doporučené produkty
grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
SMILES string
CCOP(=S)(OCC)SCSC(C)(C)C
InChI
1S/C9H21O2PS3/c1-6-10-12(13,11-7-2)15-8-14-9(3,4)5/h6-8H2,1-5H3
InChI key
XLNZEKHULJKQBA-UHFFFAOYSA-N
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General description
Terbufos is an organophosphate insecticide and nematicide, that is used extensively to control wireworms, seed corn maggots, white grubs, corn rootworm larvae, and other pests. It targets root pests that feed on corn, sugar beets, bananas, and other crops. Household uses include the control of cockroaches, houseflies, and termites along with the protection of plants of horticultural interest.
Terbufos is not approved for its use in the European Union.
Maximum residue levels (MRLs) have been set according to Reg (EC) No 149/2008 for Terbufos for various products of plant and animal origin 0.01 mg/kg.
Terbufos in its activated form irreversibly inhibits acetylcholinesterase (AChE), leading to the accumulation of acetylcholine, resulting in overstimulation of muscarinic and nicotinic receptors.
Terbufos is not approved for its use in the European Union.
Maximum residue levels (MRLs) have been set according to Reg (EC) No 149/2008 for Terbufos for various products of plant and animal origin 0.01 mg/kg.
Terbufos in its activated form irreversibly inhibits acetylcholinesterase (AChE), leading to the accumulation of acetylcholine, resulting in overstimulation of muscarinic and nicotinic receptors.
Application
The analytical standard can be used to:
- Protect and detect two thermolabile metabolites of terbufos, and simultaneously analyze terbufos and its metabolites in pepper and pepper leaf samples using GC-FPD
- Investigate photocatalytic degradation of terbufos in aqueous suspensions using titanium dioxide (TiO2) as a photocatalyst
- Study the effects of different doses of terbufos on the decomposition process and the scavenger flies assemblages composition in Wistar rat carcasses
- Measure adsorption of two commonly used organophosphorus pesticides, Phorate and Terbufos onto four tropical soils
- Examine the acute effects of terbufos and its major oxidation products, alone and in combination with each other or with atrazine, on Ceriodaphnia cf dubia
- Investigate the molecular mechanisms of genotoxicity in HepG2 cells and zebrafish embryos following exposure to terbufos, fenthion, or combinations of these pesticides
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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The mechanism of genotoxicity of the individual and combined pesticides of terbufos and fenthion were evaluated using HepG2 cells and zebrafish embryos. We determined genotoxicity by neutral comet assay and phosphorylation of H2AX (γH2AX), which indicated that cells treated with
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Terbufos is the fourth most commonly used organophosphate insecticide (OP) in the United States. Terbufos has not been demonstrated to be carcinogenic in rodents, although non-arsenical insecticides, including OPs, have been associated with excess cancer in epidemiologic studies. We investigated
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