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Key Documents

07969

Sigma-Aldrich

O-(2-Aminoethyl)polyethylene glycol 3,000

Mp 3,000

Synonyma:

Aminopolyethylene glycol

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Lineární vzorec:
NH2(CH2CH2O)nH
Číslo CAS:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.22

mol wt

Mp 3,000

Quality Level

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

α-end

amine

SMILES string

[H]OCCN

General description

O-(2-Aminoethyl)polyethylene glycol is a heterobifunctional polyethylene glycol (hydroxyl-PEG-amine) useful in conjugation and crosslinking reactions.

Application

O-(2-Aminoethyl)polyethylene glycol has been used to synthesize PEG-poly(D,L-lactide-co-glycolide) (PEG-PLGA) conjugate for use in the synthesis of PLGA-based nanoparticles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(lactic acid) (PLA) MM is synthesized via a combination of atom
Jeremiah A Johnson et al.
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Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; these materials were prepared by graft-through ROMP of drug-loaded polyethylene-glycol (PEG)
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International Journal of Pharmaceutics, 516(1-2), 61-70 (2017)
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Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics. Herein, we report the development of a new class of branched-bottlebrush polymer dual-modality organic radical contrast agents--ORCAFluors--for combined magnetic resonance and near-infrared fluorescence imaging in vivo. These nitroxide radical-based nanostructures
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Sortimentní položky

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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