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AB9042

Sigma-Aldrich

Anti-Brain Derived Neurotrophic Factor Antibody, pro

Chemicon®, from chicken

Synonyma:

proBDNF, pro BDNF

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

chicken

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_001709.3
NM_170731.3
NM_170732.3
NM_170733.2
NM_170734.2
NM_170735.4

UniProt accession no.

P23560

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... BDNF(627)

Specificity

Reacts with proBDNF. Does not recognize mature BDNF isoforms.

Immunogen

Fusion protein from mouse proBDNF containing only the prodomain region.

Application

Anti-Brain Derived Neurotrophic Factor Antibody, pro detects level of Brain Derived Neurotrophic Factor & has been published & validated for use in IP, WB, IH.
Western blot: 1:500-1:1,000. Reacts with bands of 30 kD and 28 kD.Immunohistochemistry: 1:100-1:250 on frozen sections.

Immunohistochemistry: 1:100-1:200

Immunoprecipitation: 1:100

Optimal working dilutions must be determined by the end user.

Physical form

Chicken immunoglobulin. Liquid.
Format: Semi-Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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recommended

Č. produktu
Popis
Stanovení ceny

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice.
Papaleo, F; Silverman, JL; Aney, J; Tian, Q; Barkan, CL; Chadman, KK; Crawley, JN
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Endocrinology, 157(2), 600-610 (2015-12-17)
In both mice and patients with Albright hereditary osteodystrophy, heterozygous inactivating mutations of Gsα, a ubiquitously expressed G protein that mediates receptor-stimulated intracellular cAMP production, lead to obesity and insulin resistance but only when the mutation is present on the
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Experimental neurobiology, 27(3), 155-170 (2018-07-20)
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their morphological and functional properties. Both physiological and pathological stimuli can
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Communications biology, 4(1), 1152-1152 (2021-10-07)
Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persistent synaptic strengthening invited astrocytic microdomains to convert initially internalized (pro)-brain-derived neurotrophic factor (proBDNF) into
Matteo Bergami et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(28), 11464-11478 (2013-07-12)
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