AB3430
Anti-Prosurfactant Protein B Antibody, reacts with both CT and NT
serum, Chemicon®
Synonyma:
proSP-B
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
100 μL
13 000,00 Kč
13 000,00 Kč
Očekávané datum odeslání15. března 2027podrobné informace
O této položce
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
16
Přeskočit na
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohlibiological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SFTPB(6439)
1 of 4
Tato položka | |||
|---|---|---|---|
| biological source rabbit | biological source - | biological source rabbit | biological source mouse |
| antibody form serum | antibody form purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| species reactivity human, mouse | species reactivity human | species reactivity dog, guinea pig, human, rat | species reactivity human |
| clone polyclonal | clone RM370, monoclonal, recombinant monoclonal | clone polyclonal | clone polyclonal |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Immunogen
Epitope: reacts with both C-terminus and N-terminus
Full length recombinant peptide (381 a.a.) of the human SP-B (pre)proprotein.
Application
Detect Prosurfactant Protein B using this Anti-Prosurfactant Protein B Antibody, reacts with both C-terminus & N-terminus validated for use in ELISA, IH & WB.
Immunohistochemistry: 1:4,000-1:8,000 on human tissue with and without antigen retrieval (see protocol on back) and 1:1,000-1:2,000 on adult and fetal mouse lung (see notes on back).
Immunoblot: 1:1,000-1:5,000; proprotein 42-46kDa.
ELISA: 1:500-1:1,000
Optimal dilutions must be determined by the end user.
Immunoblot: 1:1,000-1:5,000; proprotein 42-46kDa.
ELISA: 1:500-1:1,000
Optimal dilutions must be determined by the end user.
Research Category
Metabolism
Metabolism
Research Sub Category
Ion & Transport Channels
Ion & Transport Channels
Biochem/physiol Actions
Reacts strongly with human and mouse proSP-B (detects both the N-terminal and C-terminal propeptides). Does not react with mature SP-B. On human tissue immunostains alveolar Type II cells and non-ciliated bronchiolar cells. On mouse tissue immunostains alveolar Type II cells and non-ciliated bronchiolar (Clara cells) in distal and terminal airways.
Physical form
Rabbit serum. Liquid. Contains no preservative.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to twelve months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Ještě jste nenalezli správný produkt?
Vyzkoušejte náš produkt Nástroj pro výběr produktů.
Skladovací třída
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Osvědčení o analýze (COA)
Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
Jonathan M Charest et al.
Biomaterials, 52, 79-87 (2015-03-31)
The primary treatment for end-stage lung disease is lung transplantation. However, donor organ shortage remains a major barrier for many patients. In recent years, techniques for maintaining lungs ex vivo for evaluation and short-term (<12 h) resuscitation have come into
Raffaele Gerlini et al.
Cell death & disease, 10(10), 747-747 (2019-10-05)
The serine-threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) modulates important cellular functions during development, acting as a signal integrator of a wide variety of stress signals, and as a regulator of transcription factors and cofactors. We have previously demonstrated that
Mario DeFelice et al.
The Journal of biological chemistry, 278(37), 35574-35583 (2003-06-28)
Thyroid transcription factor-1 (TTF-1) is a 43-kDa, phosphorylated member of the Nkx2 family of homeodomain-containing proteins expressed selectively in lung, thyroid, and the central nervous system. To assess the role of TTF-1 and its phosphorylation during lung morphogenesis, mice bearing
Sarah E Gilpin et al.
Biomaterials, 108, 111-119 (2016-09-14)
Bio-engineered organs for transplantation may ultimately provide a personalized solution for end-stage organ failure, without the risk of rejection. Building upon the process of whole organ perfusion decellularization, we aimed to develop novel, translational methods for the recellularization and regeneration
Jeanne-Marie Krischer et al.
Histochemistry and cell biology, 155(2), 183-202 (2020-11-15)
Mechanical ventilation triggers the manifestation of lung injury and pre-injured lungs are more susceptible. Ventilation-induced abnormalities of alveolar surfactant are involved in injury progression. The effects of mechanical ventilation on the surfactant system might be different in healthy compared to
Související obsah
Active Filters
Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..
Obraťte se na technický servis