AB1566
Anti-Substance P Antibody, pain
serum, Chemicon®
Synonyma:
Anti-Hs.2563, Anti-NK2, Anti-NKNA, Anti-NPK, Anti-TAC2
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Doporučené produkty
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TAC1(6863)
Související kategorie
General description
Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapse. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.
Specificity
Substance P
Application
RIA:
1:10,000 dilution from a previous lot was used in radioimmunioassay. 80% binding detects at least 5 pg/mL.
Optimal working dilutions must be determined by the end user.
1:10,000 dilution from a previous lot was used in radioimmunioassay. 80% binding detects at least 5 pg/mL.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuroinflammation & Pain
Neuroinflammation & Pain
This Anti-Substance P Antibody, pain is validated for use in IH(P), RIA for the detection of Substance P.
Quality
Immunohistochemistry(paraffin):
Substance P (AB1566) representative staining pattern/morphology in Alzheimer’s brain. Tissue pretreated with Citrate pH6.0, antigen retrieval. Antibody diluted to 1:100.
IHC-Paraffin Staining With Citrate pH 6.0 Epitope Retrieval: Alzheimer’s Brain.
Substance P (AB1566) representative staining pattern/morphology in Alzheimer’s brain. Tissue pretreated with Citrate pH6.0, antigen retrieval. Antibody diluted to 1:100.
IHC-Paraffin Staining With Citrate pH 6.0 Epitope Retrieval: Alzheimer’s Brain.
Physical form
Rabbit polyclonal serum containing 0.1% sodium azide.
Unpurified
Storage and Stability
Stable for 1 year at -20ºC from date of receipt.
Analysis Note
Control
Spinal Cord.
Spinal Cord.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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recommended
Č. produktu
Popis
Stanovení ceny
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
Osvědčení o analýze (COA)
Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.
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Activation of spinal cord microglia and astrocytes is a common phenomenon in nerve injury pain models and is thought to exacerbate pain perception. Following a nerve injury, a transient increase in the presence of microglia takes place while the increased
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