8.51062

Dmab-OH

Novabiochem^®

• Synonyma: Dmab-OH, 4-{N-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl alcohol
• Empirický vzorec (Hillův zápis): C₂₀H₂₇NO₃
• Číslo CAS: 172611-73-3
• Molekulová hmotnost: 329.43
• MDL number: MFCD01075006
• UNSPSC Code: 12352115
• NACRES: NA.22

Vlastnosti

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥98% (TLC); ≥98.0% (HPLC)
• form: powder
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: N(c2ccc(cc2)CO)C(=C1C(=O)CC(CC1=O)(C)C)CC(C)C
• InChI: 1S/C20H27NO3/c1-13(2)9-16(21-15-7-5-14(12-22)6-8-15)19-17(23)10-20(3,4)11-18(19)24/h5-8,13,21-22H,9-12H2,1-4H3
• InChI key: GARPDGDSXTZYQQ-UHFFFAOYSA-N

Popis

General description

Reagent for the introduction of Dmab carboxylic acid protecting group. Dmab esters are stable to TFA and piperidine, but are cleaved under mild conditions by treatment with 2% hydrazine in DMF.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Linkage

Replaces: 01-63-0048

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0009)): ≥ 98 %
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable