1.37123

Benzalkonium chloride

EMPROVE^® EXPERT, Ph. Eur., JP, NF

• Synonyma: Alkylbenzyldimethylammonium chloride, Alkyldimethylbenzylammonium chloride
• Lineární vzorec: C₆H₅CH₂N(CH₃)₂RCl (R=C₈H₁₇ to C₁₈H₃₇)
• Číslo CAS: 63449-41-2
• Beilstein/REAXYS Number: 4062599
• UBA Number: 12352200
• MDL number: MFCD00145757
• UNSPSC Code: 41116107
• PubChem Substance ID: 24847423

Vlastnosti

• agency: JP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® EXPERT
• form: viscous liquid
• packaging: pkg of 1 kg
• application(s): liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• storage temp.: 15-25°C
• SMILES string: [Cl-].CCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1
• InChI: 1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1
• InChI key: TTZLKXKJIMOHHG-UHFFFAOYSA-M

Popis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Benzalkonium chloride is typically used as a preservative in liquid formulations, e.g. for topical, ophthalmic, nasal and parenteral applications. It is effective against a wide range of bacteria, yeast and fungi.
Due to a defined C12:C14 ratio with high batch-to-batch consistency, Benzalkonium chloride Emprove^® Expert provides higher solubility and antimicrobial activity. It can be used in combination with thimerosal, disodium edetate and benzyl alcohol to further increase antimicrobial activity.
This product is also available as 50% aqueous solution (Art.No. 137124).

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Bezpečnostní informace

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H314,H410
• pcodes: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 2