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Z-003

Supelco

Zopiclone solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirický vzorec (Hillův zápis):
C17H17ClN6O3
Číslo CAS:
43200-80-2
Molekulová hmotnost:
388.81
EC Number:
200-835-2
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C[NH+]1CCN(CC1)C(=O)OC2N(C(=O)c3nccnc23)c4ccc(Cl)cn4

InChI

1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/p+1

InChI key

GBBSUAFBMRNDJC-UHFFFAOYSA-O

General description

A certified solution standard suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, pharmaceutical research, or urine drug testing.  Zopiclone is a non-benzodiazepine hypnotic sold under the trade names Imovane® and ZImovane® and is prescribed for the treatment of insomnia.

Application

  • Zopiclone solution pharmacological research applications: Utilized in developing and validating analytical methods for detecting z-drugs in biological samples, enhancing forensic toxicology and clinical diagnostics (Chauhan et al., 2024).
  • Zopiclone as a GABA receptor modulator in biochemistry: Investigated for its role in drug-facilitated crimes, particularly its identification through presumptive spot tests, which is crucial for forensic analysis (Chauhan and Sharma, 2023).
  • Zopiclone solution for sleep disorder experimental studies: Analyzed for its effects on hyperlipidemic conditions in postmortem blood, contributing to forensic science and medical research (Elenstål et al., 2023).
  • Zopiclone liquid formulation stability in laboratory conditions: Reviewed for long-term medication use in insomnia treatments, providing essential data on clinical safety and efficacy (Zee et al., 2023).
  • Zopiclone in vitro receptor binding assays methodology: Employed in evaluating the toxicity of zopiclone impurities, supporting the development of safer pharmaceutical products (Yin et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Imovane is a registered trademark of Sanofi-Aventis
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Č. produktu
Popis
Stanovení ceny

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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F Hoffmann
Swiss medical weekly, 143, w13745-w13745 (2013-01-26)
In many countries newer non-benzodiazepines, zolpidem and zopiclone ("Z-drugs"), are prescribed instead of benzodiazepine hypnotics. This is not supported by current evidence and guidelines. The aim of this study was to compare the perceptions of GPs on the benefits and
Nico J Diederich et al.
Journal of the neurological sciences, 314(1-2), 12-19 (2011-11-29)
Sleep symptoms in Parkinson's disease (PD) are frequent and have multifactorial and multilayered causes. Primary involvement of sleep/wake regulating centers in the brainstem, sleep problems caused by the nocturnal manifestation of motor and dysautonomic signs and medication-induced sleep problems are
Milena Araújo Tonon et al.
Analytical and bioanalytical chemistry, 405(1), 267-273 (2012-11-07)
A new high-performance liquid chromatographic method with triple quadrupole mass spectrometry detection was developed and validated for the quantification of zopiclone enantiomers in rat brain samples. Zopiclone enantiomers were resolved on a CHIRALPAK AD column with a mobile phase consisting
Coma after single dose of zopiclone.
Annelie K Hintzen et al.
The American journal on addictions, 21(3), 291-291 (2012-04-13)
To breathe, perchance not to wake?
David M Rapoport
Journal of applied physiology (Bethesda, Md. : 1985), 112(2), 247-248 (2011-10-29)
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