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Key Documents

890860C

Avanti

14:0 TAP

Avanti Research - A Croda Brand 890860C

Synonyma:

1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C34H68NO4Cl
Číslo CAS:
Molekulová hmotnost:
590.36
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (890860C-25mg)
pkg of 2 × 4 mL (890860C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 890860C

concentration

10 mg/mL (890860C-25mg)
25 mg/mL (890860C-200mg)

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

General description

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

Application

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

Biochem/physiol Actions

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Clear Glass Sealed Ampule (890860C-200mg)
5 mL Clear Glass Sealed Ampule (890860C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


Osvědčení o analýze (COA)

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Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
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Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
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In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
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