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860678P

Avanti

C24 Ceramide-d7 (d18:1-d7/24:0)

Avanti Research - A Croda Brand 860678P, powder

Synonyma:

N-lignoceroyl-D-erythro-sphingosine (d7)

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C42H76D7NO3
Číslo CAS:
Molekulová hmotnost:
657.16
UNSPSC Code:
12352100
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860678P-1mg)
pkg of 1 × 5 mg (860678P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860678P

shipped in

dry ice

storage temp.

−20°C

General description

C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).

Application

C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.

Biochem/physiol Actions

C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860678P-1mg)
5 mL Amber Glass Screw Cap Vial (860678P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available


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Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
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