857324P

17:0 Cyclic LPA

Avanti Research^™ - A Croda Brand 857324P, powder

• Synonyma: 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt)
• Empirický vzorec (Hillův zápis): C₂₀H₄₂NO₆P
• Číslo CAS: 2260669-82-5
• Molekulová hmotnost: 423.52
• UNSPSC Code: 51191904
• NACRES: NA.25

Vlastnosti

• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (857324P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 857324P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]

Popis

General description

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate.

Application

17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).

Biochem/physiol Actions

cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

Packaging

5 mL Amber Glass Screw Cap Vial (857324P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• flash_point_f: No data available
• flash_point_c: No data available