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850520P

Avanti

n-dodecyl-β-D-maltoside (DDM)

Avanti Research™ - A Croda Brand

Synonyma:

DDM; lauryl maltoside; dodecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirický vzorec (Hillův zápis):
C24H46O11
Číslo CAS:
69227-93-6
Molekulová hmotnost:
510.62
MDL number:
MFCD00043012
UNSPSC Code:
12161902
NACRES:
NA.25

description

n-dodecyl-β-D-maltopyranoside

assay

>99% (contains <2% alpha isomer, TLC)

form

powder

mol wt

510.62 g/mol

packaging

pkg of 1 × 1 g (850520P-1g)
pkg of 1 × 25 g (850520P-25g)
pkg of 1 × 5 g (850520P-5g)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

General description

n-dodecyl-β-D-maltoside (DDM) is a sugar-based surfactant.
DDM is the most widely used detergent for the isolation and purification of GPCR′s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.

Application

n-dodecyl-β-D-maltoside (DDM) has been used to solubilize mitochondrial extracts of fibroblasts to perform one-dimensional blue-native PAGE (BN-PAGE) analysis for assembled oxidative phosphorylation (OXPHOS) complexes.

Biochem/physiol Actions

n-dodecyl-β-D-maltoside (DDM) exhibits biocompatibility and biodegradability. It serves as a facilitator of electron transfer in order to decrease the oxidation potential of 3,4-ethylenedioxythiophene (EDOT). It can also increase the solubility of EDOT in aqueous solution.

Packaging

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)
20 mL Clear Glass Screw Cap Vial (850520P-1g)
30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Č. produktu
Popis
Stanovení ceny

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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LacY mutant Cys154 → Gly exhibits a periplasmic-closed crystal structure identical to the WT, but is periplasmic-open in the membrane. The mutant hardly catalyzes transport, but binds galactosides from either side of the membrane with the same affinity and is
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