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810133C

Avanti

18:1-12:0 NBD PC

Avanti Research™ - A Croda Brand 810133C

Synonyma:

1-Oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine

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About This Item

Empirický vzorec (Hillův zápis):
C44H76N5O11P
Číslo CAS:
190792-36-0
Molekulová hmotnost:
882.07
MDL number:
MFCD22495265
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810133C-1mg)
pkg of 5 × 1 mL (810133C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810133C

concentration

1 mg/mL (810133C-1mg)
1 mg/mL (810133C-5mg)

lipid type

fluorescent lipids
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a prime metabolite in eukaryotes glycerolipid metabolism, mainly synthesized in liver. It is a major element of lipoproteins, bile and lung surfactant. NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.

Application

18:1-06:0 NBD PC is suitable for:
  • the generation giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy
  • labelling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy
  • the preparation of phospholipid-coated beads

Biochem/physiol Actions

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent analog in biological membranes in order to study the cellular processes.

Packaging

5 mL Amber Glass Screw Cap Vial (810133C-1mg)
5 mL Amber Glass Screw Cap Vial (810133C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

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Osvědčení o analýze (COA)

Lot/Batch Number

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Wan-Chen Lin et al.
Biophysical journal, 90(1), 228-237 (2005-10-11)
A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the formation of ordered phase domains in one leaflet that are compositionally different from the opposing leaflet of the bilayer. Using model membrane systems, many previous studies have demonstrated the
Laura K Cole et al.
Biochimica et biophysica acta, 1821(5), 754-761 (2011-10-08)
Phosphatidylcholine (PC) is the major phospholipid component of all plasma lipoprotein classes. PC is the only phospholipid which is currently known to be required for lipoprotein assembly and secretion. Impaired hepatic PC biosynthesis significantly reduces the levels of circulating very
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