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791281P

Avanti

α-mycolic acid, methoxy cis

powder

Synonyma:

Cyclopropaneeicosanoic acid, β-hydroxy-2-[(17S,18S)-17-methoxy-18-methylhexatriacontyl]-α-tetracosyl-, (αR,βR,1R,2S)-

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About This Item

Empirický vzorec (Hillův zápis):
C85H168O4
Číslo CAS:
23599-54-4
Molekulová hmotnost:
1254.24
MDL number:
MFCD00870345
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (791281P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 791281P

lipid type

bacterial lipids

shipped in

dry ice

storage temp.

−20°C

General description

α-mycolic acid (MA), methoxy cis comprises 84–88 carbon atoms like the other types keto and hydroxy MA. All the MA types are synthesized from hydroxylated intermediate, with methoxy M generated by the action of enzyme methoxylase.
Mycolic acid is a long Fatty acid found in the cell walls of the mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis.

Biochem/physiol Actions

Methoxy mycolic acids are antigenic and are specific for pathogenic mycobacterial class. The three types of mycolic acids including the methoxy-MA display variation in their antigenicity with reference to antibody recognition.

Packaging

5 mL Amber Glass Screw Cap Vial (791281P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Navštívit knihovnu dokumentů

Nabil Tahiri et al.
Angewandte Chemie (International ed. in English), 59(19), 7555-7560 (2020-02-19)
In Mycobacterium tuberculosis, mycolic acids and their glycerol, glucose, and trehalose esters ("cord factor") form the main part of the mycomembrane. Despite their first isolation almost a century ago, full stereochemical evaluation is lacking, as is a scalable synthesis required
Hedia Marrakchi et al.
Chemistry & biology, 21(1), 67-85 (2014-01-01)
Mycolic acids are major and specific lipid components of the mycobacterial cell envelope and are essential for the survival of members of the genus Mycobacterium that contains the causative agents of both tuberculosis and leprosy. In the alarming context of
Heena Ranchod et al.
PloS one, 13(8), e0200298-e0200298 (2018-08-10)
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-MA, each with specific biological functions and conformational characteristics. Antibodies in tuberculosis (TB) patient sera respond

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