I9760

Iodoacetic acid N-hydroxysuccinimide ester

for peptide synthesis

• Synonyma: N-Hydroxysuccinimide iodoacetate, N-Iodoacetoxysuccinimide
• Empirický vzorec (Hillův zápis): C₆H₆INO₄
• Číslo CAS: 39028-27-8
• Molekulová hmotnost: 283.02
• UNSPSC Code: 12352005
• PubChem Substance ID: 57654310
• NACRES: NA.22
• MDL number: MFCD00058451

Vlastnosti

• Název produktu: Iodoacetic acid N-hydroxysuccinimide ester, powder
• form: powder
• Quality Segment: 200
• reaction suitability: reagent type: cross-linking reagent
• solubility: DMF: 50 mg/mL
• application(s): peptide synthesis
• functional group: NHS ester
• storage temp.: −20°C
• SMILES string: O=C(N1OC(CI)=O)CCC1=O
• InChI: 1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
• InChI key: VRDGQQTWSGDXCU-UHFFFAOYSA-N

Popis

Application

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 2-atom linker.

Disclaimer

The iodoacetyl group is light sensitive.

Bezpečnostní informace

• Piktogramy: GHS07
• Výstražné slovo: Warning
• Kódy nebezpečí: H315,H319,H335
• Bezpečnostní pokyny: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Cílové orgány: Respiratory system
• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 3
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable
• PPE (osobní ochranné prostředky): dust mask type N95 (US), Eyeshields, Gloves