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928135

Sigma-Aldrich

Gold nanoparticles

60 nm diameter, Alkyne functionalized, 1 ML, OD 50, in water

Synonyma:

AuNP, GdNP, Gold NP

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.22

Quality Level

100

description

Alkyne surface density: 1/nm2

concentration

in water

OD

50

core diam.

60 nm , coefficient of variance <12%

diameter

60 nm

λmax

540 nm

PDI

<0.200

functional group

alkyne

storage temp.

2-8°C

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any azide-tagged molecule through Cu(I)-catalyzed click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.
Alkyne functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Storage and Stability

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

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Gold nanoparticles: synthesis and applications in drug delivery.
Khan A K, et al.
Tropical Journal of Pharmaceutical Research, 1169-1177 (2014)
Wilson Luo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(5), 1052-1059 (2016-10-12)
In this study, we report the design, synthesis, and characterization of small 3 nm water soluble gold nanoparticles (AuNPs) that feature cyclopropenone-masked strained alkyne moieties capable of undergoing interfacial strain-promoted cycloaddition (i-SPAAC) with azides after exposure to UV-A light. A strained
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