901904

tBuXPhos

95%, powder or crystals

• Synonyma: 2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl, t-Bu XPhos, tert-Butyl XPhos
• Empirický vzorec (Hillův zápis): C₂₉H₄₅P
• Číslo CAS: 564483-19-8
• Molekulová hmotnost: 424.64
• NACRES: NA.22
• UNSPSC Code: 12352002
• MDL number: MFCD06411306

Vlastnosti

• Název produktu: tBuXPhos, 95%
• assay: 95%
• form: powder or crystals
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst; reaction type: Cross Couplings, reagent type: ligand
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 148-151 °C (lit.), 150 °C
• functional group: phosphine
• greener alternative category: Aligned
• SMILES string: CC(P(C(C=CC=C1)=C1C(C(C(C)C)=CC(C(C)C)=C2)=C2C(C)C)C(C)(C)C)(C)C
• InChI: 1S/C29H45P/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12/h13-21H,1-12H3
• InChI key: SACNIGZYDTUHKB-UHFFFAOYSA-N

Popis

General description

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives. This bulky dialkylbiaryl phosphine (Buchwald ligand) is used for palladium-catalyzed Buchwald-Hartwig amination and Suzuki-Miyaura coupling reactions. Its large cone angle promotes formation of highly reactive monoligated species, providing exceptional activity for challenging C-N and C-C bond-forming reactions, thus aligning with Green Chemistry principle "Catalysis". Click here for more information.

tBuXPhos [2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Application

tBuXPhos has been used in the preparation of [tBuXPhosAu(MeCN)]BAr₄F, a gold catalyst for the intermolecular [2+2] cycloaddition of terminal arylalkynes with substituted alkenes to form functionalized cyclobutenes with high regioselectivity.

Legal Information

Usage subject to Patents: EP 1097158; JP 5758844; CA 2336691

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable