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852228

2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate

Name: 2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate
Brand: ALDRICH

≥98%

Synonyma:

2′-Deoxy-5′-guanylic acid disodium salt, 5′-dGMP disodium salt

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen

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About This Item

Empirický vzorec (Hillův zápis):

C₁₀H₁₂N₅Na₂O₇P · xH₂O

Číslo CAS:

33430-61-4

Molekulová hmotnost:

391.18 (anhydrous basis)

MDL number:

MFCD00150758

UNSPSC Code:

41106305

PubChem Substance ID:

24888319

NACRES:

NA.22

Doporučené produkty

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Sigma-Aldrich

D9500

2′-Deoxyguanosine 5′-monophosphate sodium salt hydrate

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D6375

2′-Deoxyadenosine 5′-monophosphate

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T7004

Thymidine 5′-monophosphate disodium salt hydrate

Sigma-Aldrich

D4010

2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate

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D3876

2′-Deoxyuridine 5′-monophosphate disodium salt

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D7750

2′-Deoxycytidine 5′-monophosphate

Sigma-Aldrich

471283

Triethylamine

Sigma-Aldrich

D7625

2′-Deoxycytidine 5′-monophosphate sodium salt

Sigma-Aldrich

852198

2′-Deoxyadenosine 5′-monophosphate monohydrate

Sigma-Aldrich

G8377

Guanosine 5′-monophosphate disodium salt hydrate

Quality Level

100

assay

≥98%

form

solid

impurities

≤4% ethanol

mp

>245 °C (dec.) (lit.)

SMILES string

[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1

InChI

1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1

InChI key

HQSJCEYJAGVPJG-BIHLCPNHSA-L

Application

Reactant involved in:

Analysis of self-assembling in solution and nucleation / growth of G-qudruplexes
Nucleophilic trapping
Reductive alkylation

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Roche

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Adenosine 5′-monophosphate disodium salt

Extracellular dGMP enhances Deinococcus radiodurans tolerance to oxidative stress.

Mingfeng Li et al.

PloS one, 8(1), e54420-e54420 (2013-02-01)

Free extracellular DNA provides nutrition to bacteria and promotes bacterial evolution by inducing excessive mutagenesis of the genome. To understand the influence of extracellular DNA fragments on D. radiodurans, we investigated cell growth and survival after extracellular DNA or dNMPs

Enhanced resolution of molecular recognition to distinguish structurally similar molecules by different conformational responses of a protein upon ligand binding.

Mariko Higuchi et al.

Journal of structural biology, 173(1), 20-28 (2010-10-05)

MutT distinguishes substrate 8-oxo-dGTP from dGTP and also 8-oxo-dGMP from dGMP despite small differences of chemical structures between them. In this paper we show by the method of molecular dynamics simulation that the transition between conformational substates of MutT is

Ciprofloxacin photosensitized oxidation of 2'-deoxyguanosine-5'-monophosphate in neutral aqueous solution.

Yancheng Liu et al.

Photochemistry and photobiology, 88(3), 639-644 (2012-02-11)

Laser flash photolysis studies have been carried out to investigate the reactions of ciprofloxacin (CPX) with 2'-deoxyguanosine-5'-monophosphate (dGMP), N, N, N', N'-tetramethyl-p-phenylenediamine (TMPD) and ferulic acid (FCA) in neutral aqueous solutions, respectively. CPX triplet state ((3)CPX*) can be quenched by

The exceptional properties of Plasmodium deoxyguanylate pathways as a potential area for metabolic and drug discovery studies.

Mahmoud Kandeel et al.

Nucleic acids symposium series (2004), (53)(53), 39-40 (2009-09-15)

In Plasmodium falciparum, deoxyguanylate was found to be a substrate for several DNA metabolizing enzymes. Guanylate kinase utilizes dGMP with very low specificity, which is estimated to be the lowest among well-known prokaryotic and eukaryotic enzymes. Furthermore, thymidylate kinase, which

Photosensitizing properties of biopterin and its photoproducts using 2'-deoxyguanosine 5'-monophosphate as an oxidizable target.

Mariana P Serrano et al.

Physical chemistry chemical physics : PCCP, 14(33), 11657-11665 (2012-07-25)

UV-A radiation (320-400 nm) induces damage to the DNA molecule and its components through photosensitized reactions. Biopterin (Bip) and its photoproducts 6-formylpterin (Fop) and 6-carboxypterin (Cap) accumulate in the skin of human beings suffering from vitiligo, a depigmentation disorder where

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Hlavní dokumenty

2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate

≥98%

About This Item

Doporučené produkty

Vlastnosti

Quality Level

assay

form

impurities

mp

SMILES string

InChI

InChI key

Popis

Application

Bezpečnostní informace

Storage Class

wgk_germany

flash_point_f

flash_point_c

Dokumentace

Osvědčení o analýze (COA)

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