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202452

Sigma-Aldrich

Poly(ethylene glycol)

average MV 8,000, hydroxyl

Synonyma:

Polyethylene glycol, PEG

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About This Item

Lineární vzorec:
H(OCH2CH2)nOH
Číslo CAS:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24852065
NACRES:
NA.23

product name

Poly(ethylene glycol), average Mv ~8,000, powder (crystalline)

form

powder (crystalline)

mol wt

average Mv ~8,000

viscosity

800 cSt(210 °F)(lit.)

mp

60-63 °C (lit.)

density

1.27 g/mL at 25 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application

  • PEG in Targeted Drug Delivery: Investigating the effects of PEGylation on the surface properties of nanoparticles, which plays a crucial role in targeted drug delivery systems (Shi et al., 2021).
  • PEG′s Role in Nanomedicine: Discussing the immunological properties of PEG and exploring its popular role in nanomedicine formulations, with a focus on immunogenic responses (Shi et al., 2022).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Osvědčení o analýze (COA)

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Developing a high-efficiency manufacturing system for personalized medicine plays an important role in increasing the feasibility of personalized medication. The purpose of this study is to investigate the feasibility of a new extrusion-based fabrication process for personalized drugs with a
Olivia Tort et al.
Journal of lipid research, 59(11), 2108-2115 (2018-09-15)
Cholesterol efflux (CE) capacity has been inversely associated with atherosclerosis and may provide an insight on inflammation occurring in human immunodeficiency virus (HIV) individuals. We address this by studying CE in HIV patients at different stages of HIV disease progression.
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
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