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181986

Sigma-Aldrich

Poly(ethylene oxide)

average MV 100,000 (nominal), powder, hydroxyl, BHT as inhibitor

Synonyma:

Polyethylene oxide, PEO

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About This Item

Lineární vzorec:
(-CH2CH2O-)n
Číslo CAS:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24850968
NACRES:
NA.23

product name

Poly(ethylene oxide), average Mv 100,000 (nominal), powder

form

powder

mol wt

average Mv 100,000 (nominal)

contains

200-500 ppm BHT as inhibitor

refractive index

n20/D 1.4539

viscosity

12-50 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

transition temp

Tg −67 °C
Tm 65 °C

density

1.13 g/mL at 25 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene oxide) is a non-ionic hydrophilic linear polymer. It can be prepared by catalytic polymerization of ethylene oxide. Owing to its hydration and swelling properties, it is widely used in controlled drug delivery systems and bioadhesive materials.

Application

PEO can be used to:
  • Prepare polymer brushes with unique wormlike conformation which can be used in cancer drug delivery systems.
  • Synthesize polymer electrolytes for solid-state batteries and fuel cells.
  • Prepare biodegradable PEO/Ag nanocomposites forbiomedical and food packaging applications.

Features and Benefits

  • High water solubility
  • Non-toxicity
  • Rapid hydration
  • Insensitive to pH of the physiological system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

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Sortimentní položky

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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