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135828

Sigma-Aldrich

Benzamide

99%

Synonyma:

Benzoic acid amide

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
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About This Item

Lineární vzorec:
C6H5CONH2
Číslo CAS:
55-21-0
Molekulová hmotnost:
121.14
Beilstein/REAXYS Number:
385876
EC Number:
200-227-7
MDL number:
MFCD00007968
UNSPSC Code:
12352100
PubChem Substance ID:
24848219
NACRES:
NA.22

assay

99%

mp

125-128 °C (lit.)

solubility

ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to light yellow

SMILES string

NC(=O)c1ccccc1

InChI

1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)

InChI key

KXDAEFPNCMNJSK-UHFFFAOYSA-N

Gene Information

human ... PARP1(142)

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General description

Benzamide on radioiodination by different labeling procedures results in large-scale production of radioiodinated benzamides having potential therapeutic application for patients with metastatic malignant melanoma.

Benzamide is used as a building block in organic synthesis for the preparation of various biologically active compounds.

Application

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. It was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Biochem/physiol Actions

Inhibits poly(ADP-ribose) polymerase (PARP).

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H341

Hazard Classifications

Acute Tox. 4 Oral - Muta. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

356.0 °F - closed cup

flash_point_c

180 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Osvědčení o analýze (COA)

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Chapter One-Recent Advances in Cancer Therapeutics
Nicola, et al.
Progress in Medicinal Chemistry, 54 null
Walter Mier et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(1), 9-14 (2013-11-28)
The performance of cytotoxic drugs is defined by their selectivity of uptake and action in tumor tissue. Recent clinical responses achieved by treating metastatic malignant melanoma with therapeutic modalities based on gene expression profiling showed that malignant melanoma is amenable
Photocatalytic Decompositions of Carboxylic Acid Derivatives by Semiconductors.
Park KH and Kim JH.
Bull. Korean Chem. Soc., 12(4), 439-439 (1991)
Willian G Birolli et al.
Pesticide biochemistry and physiology, 156, 129-137 (2019-04-28)
Chiral pesticides have been used in agriculture, including (±)-lambda-cyhalothrin ((±)-LC), which is a pyrethroid insecticide widely employed on crops for protection against different types of insects. However, enantioselectivity is poorly studied in biodegradation processes. Therefore, the (±)-LC enantioselective biodegradation by
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Biotechnology journal, 4(4), 510-516 (2009-03-18)
A (+)-gamma-lactamase was precipitated, cross-linked and the resulting solid crushed prior to immobilisation within a capillary column microreactor. The microreactor was subsequently used to study enzyme stability, activity, kinetics and substrate specificity. The thermophilic (+)-gamma-lactamase retained 100% of its initial
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