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N9877

Sigma-Aldrich

Nitrilotriacetic acid

Sigma Grade, ≥99%

Synonym(s):

N,N-Bis(carboxymethyl)glycine, NTA, Tris(carboxymethyl)amine

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About This Item

Linear Formula:
N(CH2COOH)3
CAS Number:
139-13-9
Molecular Weight:
191.14
Beilstein:
1710776
EC Number:
205-355-7
MDL number:
MFCD00004287
UNSPSC Code:
12352106
PubChem Substance ID:
24897916
NACRES:
NA.31

grade

Sigma Grade

Quality Level

200

Assay

≥99%

form

powder

reaction suitability

reagent type: reductant

pH

1.7-2.7 (23 °C, 10 g/L)

mp

245 °C (dec.) (lit.)

solubility

1 M NaOH: 100 mg/mL, clear to very slightly hazy, colorless to light yellow

SMILES string

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChI key

MGFYIUFZLHCRTH-UHFFFAOYSA-N

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Application

An excellent chelating agent.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H319,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

212.0 °F - closed cup

Flash Point(C)

100 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT9955
MKCS9058
MKCS9057
MKCS4599
MKCM6783

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Matti F Pronker et al.
The Journal of biological chemistry, 290(24), 15092-15101 (2015-04-24)
Olfactomedin-1 (Olfm1; also known as noelin and pancortin) is a member of the olfactomedin domain-containing superfamily and a highly expressed neuronal glycoprotein important for nervous system development. It binds a number of secreted proteins and cell surface-bound receptors to induce
Hui Xu et al.
Biosensors & bioelectronics, 41, 90-95 (2012-09-11)
A label-free and highly sensitive impedimetric aptasensor was developed based on electropolymerized film for the determination of thrombin. The first step is the electrogeneration of a poly(pyrrole-nitrilotriacetic acid) (poly(pyrrole-NTA)) film onto the surface of electrodes followed by complexation of Cu(2+)
Li Jiang et al.
The Journal of pathology, 228(3), 366-377 (2012-08-07)
Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the commercially used types of asbestos (chrysotile, crocidolite, and amosite), the carcinogenicity of chrysotile is not fully appreciated. Here, we show that all three asbestos types similarly
R L Anderson et al.
Critical reviews in toxicology, 15(1), 1-102 (1985-01-01)
This article provides a review of available information on the chemistry, environmental toxicology, and mammalian toxicology of nitrilotriacetic acid (NTA). The ability of NTA to chelate metal ions such as Mg++ and Ca++ into water soluble complexes makes NTA useful
Asgar Abbas Kazrani et al.
Nucleic acids research, 42(9), 5929-5936 (2014-03-19)
PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although
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