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374776

Sigma-Aldrich

4-Methoxybiphenyl

97%

Synonym(s):

4-Phenylanisole

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About This Item

Linear Formula:
C6H5C6H4OCH3
CAS Number:
Molecular Weight:
184.23
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Assay

97%

form

powder, crystals or chunks

mp

86-90 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

COc1ccc(cc1)-c2ccccc2

InChI

1S/C13H12O/c1-14-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-10H,1H3

InChI key

RHDYQUZYHZWTCI-UHFFFAOYSA-N

Application

4-Methoxybiphenyl has been used as a standard reagent whose fluorescence intensity is associated with the fluorescence characteristics of the products of derivatization reaction for aryl halides with phenylboronic acid (PBA).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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P Paterson et al.
Xenobiotica; the fate of foreign compounds in biological systems, 15(6), 493-502 (1985-06-01)
The rate of production of 4-hydroxybiphenyl from 4-methoxybiphenyl in hepatocytes isolated from untreated rats was essentially identical to that from biphenyl in hepatocytes isolated from rats pretreated with beta-naphthoflavone at 40 mg/kg. Similar results were obtained using liver microsomes isolated
Influence of the sulphation inhibitor, 2,6-dichloro-4-nitrophenol, on the production and conjugation, of 4-hydroxybiphenyl generated from 4-methoxybiphenyl by rat isolated hepatocytes.
J R Fry et al.
Biochemical pharmacology, 36(18), 3090-3092 (1987-09-15)
J R Fry
Xenobiotica; the fate of foreign compounds in biological systems, 17(6), 751-758 (1987-06-01)
1. The metabolism of 4-methoxybiphenyl to 4-hydroxybiphenyl and its sulphate and glucuronic acid conjugates has been studied in rat isolated hepatocytes at various concentrations of 4-methoxybiphenyl. 2. The proportions of metabolites produced remained constant at concentrations of 4-methoxybiphenyl less than
A comparison of biphenyl 4-hydroxylation and 4-methoxybiphenyl O-demethylation in rat liver microsomes.
J R Fry
Biochemical pharmacology, 30(14), 1915-1919 (1981-07-15)

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