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Key Documents

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1370600

USP

Lovastatin

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Mevinolin

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About This Item

Fórmula empírica (notación de Hill):
C24H36O5
Número de CAS:
75330-75-5
Peso molecular:
404.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key

PCZOHLXUXFIOCF-BXMDZJJMSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lovastatin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Lovastatin Tablets
  • Simvastatin
  • Simvastatin Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

1370611

Lovastatin Related Compound A, United States Pharmacopeia (USP) Reference Standard

L0790000

Lovastatin, European Pharmacopoeia (EP) Reference Standard

Y0001136

Lovastatin for peak identification, European Pharmacopoeia (EP) Reference Standard

1370655

Lovastatin Impurity Identification Mixture, United States Pharmacopeia (USP) Reference Standard

1236833

Lovastatin Epimer Mixture, United States Pharmacopeia (USP) Reference Standard

1443216

Mevastatin, United States Pharmacopeia (USP) Reference Standard

PHR2240

Mevastatin/Lovastatin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2278

Lovastatin Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2279

Lovastatin Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2277

Lovastatin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Dae-Hyoung Yoo et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1508-1513 (2014-06-21)
Orally administered drugs may be metabolized by intestinal microbial enzymes before absorption into the blood. Accordingly, coadministration of drugs affecting the metabolic activities of gut microbes (e.g., antibiotics) may lead to drug-drug interactions (DDI). In this study, gut microbiota-mediated DDI
Keith G Tolman
The American journal of cardiology, 89(12), 1374-1380 (2002-06-14)
The cholesterol-lowering agents, known as statins, have been in use for 15 years and are among the most commonly prescribed drugs. Animal studies and premarketing clinical trials have given signals of hepatotoxicity, primarily minor elevations in serum alanine aminotransferase enzyme
Eli E Bar et al.
Expert opinion on investigational drugs, 17(2), 185-195 (2008-01-31)
Pediatric brain tumors are the most common cause of cancer-related death in children. Despite advances in neuroimaging, surgical techniques, radiotherapy and the introduction of new chemotherapeutic agents, up to 30% of all patients diagnosed with medulloblastoma will die from their
D S Alejandro et al.
Journal of the American Society of Nephrology : JASN, 5(2), 153-160 (1994-08-01)
Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other
Enrico Peiretti et al.
Experimental eye research, 124, 11-16 (2014-05-06)
Starting from previous studies showing that patients with cognitive deficit present neutral lipids (NLs) accumulation in cytoplasm of their peripheral blood mononuclear cells (PBMCs) and considering that there is epidemiological evidence linking age-related macular degeneration (AMD) to cognitive deficit, the
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